CD47 Diagram och kurser — TradingView

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About InVivoMAb anti-mouse/human/rat CD47 (IAP). The MIAP410 monoclonal antibody reacts with mouse CD47 otherwise known as integrin-associated protein (IAP). CD47 is an approximately 50 kDa glycosylated five transmembrane protein that is ubiquitously expressed by both hematopoietic cells such as T and B lymphocytes, monocytes, platelets and erythrocytes and non-hematopoietic cells. Purified anti-mouse CD47 Antibody - CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. 2021-03-09 · CD47 is a 50-kDa transmembrane surface protein with an extracellular IgV domain that is ubiquitously expressed at varying levels across all cell types (2, 3). CD47 is a potent “don’t eat me” signal regulating programed cell removal (PrCR) (4, 5).

Cd47

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CD47 is an immunoglobulin-like transmembrane protein displayed on the surface of nearly all normal, healthy cells in the body as a “don't eat me” signal to Abstract. CD47 on erythrocytes inhibits phagocytosis through interaction with the inhibitory immunoreceptor SIRPα expressed by macrophages. Thus, the CD47 (Myc-DDK-tagged)-Human CD47 molecule (CD47), transcript variant 2.

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CD47 (also called integrin-associated protein) is the “receptor” for TSP1 and the “ligand” for SHP-1-recruiting inhibitory immunoreceptor signal regulatory protein (SIRPα), also known as MFR and CD172a.

2021-03-04 · CD47 is a cell surface glycoprotein expressed on a wide variety of cells. It is a receptor for thrombospondin-1 and a counter-receptor for the signal regulatory protein-α (SIRPα). Tissue distribution and regulation of CD47 and binding partners .
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Macrophages as components of the innate immune system play a critical role in antitumor responses. Strategies for targeting CD47 are becoming a hot spot for cancer therapy.

Inläsare: Anders Jacobsson.
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The MIAP410 monoclonal antibody reacts with mouse CD47 otherwise known as integrin-associated protein (IAP). CD47 is an approximately 50 kDa glycosylated five transmembrane protein that is ubiquitously expressed by both hematopoietic cells such as T and B lymphocytes, monocytes, platelets and erythrocytes and non-hematopoietic cells. Purified anti-mouse CD47 Antibody - CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. 2021-03-09 · CD47 is a 50-kDa transmembrane surface protein with an extracellular IgV domain that is ubiquitously expressed at varying levels across all cell types (2, 3). CD47 is a potent “don’t eat me” signal regulating programed cell removal (PrCR) (4, 5). Lack of CD47 expression promotes a markedly accelerated development of spontaneous AIHA in the autoimmune-prone nonobese diabetic mice and results in increased sensitivity to experimental AIHA induced by both IgG1 and IgG2a anti-RBC monoclonal autoantibodies in nonautoimmune C57BL/6 mice. 19 We have previously suggested that, since CD47 is expressed on virtually all cells in the host, but not CD47 is a highly glycosylated, ~50 kDa membrane protein.

Anti-CD47 Mouse Monoclonal Antibody [clone: 3H1457] VWR

Undertitel: [Ångestpodden]. Av: Höckerstrand, Ida. Språk: Svenska. Publiceringsår: 2019. Klassifikation: Personlig utveckling och träning.

LIBRIS titelinformation: Role of the CD47/SIRPα-interaction in regulation of macrophage phagocytosis / Mattias Olsson.